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Symbol Name ID |
Hif1a
hypoxia inducible factor 1, alpha subunit MGI:106918 |
| Darker colors indicate more annotations |
| Mouse Phenotypes | abnormal brain vasculature morphology |
decreased neuron apoptosis |
open neural tube |
decreased susceptibility to ischemic brain injury |
increased susceptibility to ischemic brain injury |
increased cerebral infarct size |
abnormal cortical plate morphology |
hydrocephaly |
increased hindbrain size |
enlarged lateral ventricles |
loss of hippocampal neurons |
abnormal cerebral hemisphere morphology |
abnormal cerebral cortex morphology |
loss of cortex neurons |
abnormal occipital lobe morphology |
abnormal temporal lobe morphology |
abnormal innervation pattern to muscle |
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| Availability | Mouse Genotype | |||||||||||||||||
| Hif1atm1Jhu/Hif1atm1Jhu | ||||||||||||||||||
| Hif1atm1Pec/Hif1atm1Pec | ||||||||||||||||||
| Hif1atm1Rsjo/Hif1a+ | ||||||||||||||||||
| Hif1atm3Rsjo/Hif1atm3Rsjo Tg(Ckmm-cre)5Khn/? (conditional) |
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| Hif1atm3Rsjo/Hif1atm3Rsjo Tg(Camk2a-cre)2Szi/0 (conditional) |
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| Hif1atm3Rsjo/Hif1atm3Rsjo Tg(Camk2a-cre)1Szi/0 (conditional) |
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| Hif1atm1Stom/Hif1atm1.1Stom Tg(Nes-cre)1Kag/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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